OPEN and CLOSED state of SPIKE SARS-COV-2: relationship with some integrin binding. A biological molecular approach to better understand the coagulant effect

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Submitted: May 18, 2021
Published: Jun 2, 2021
DOI: 10.29328/journal.abb.1001028
Keywords:
SPIKE, RGD, Integrin, Coagulation, Quantitative effect, Molecular approach

Main Article Content

Luisetto M
IMA Marijnskaya Academy, Applied Pharmacologist, Natural Science Branch, 29121 Italy
Khaled Edbey
Professor, Department of Chemistry, University of Benghazi, Libya
Mashori GR
Professor, Department of Medical & Health Sciences for Woman, Peoples University of Medical and Health Sciences for Women, Pakistan
Yesvi AR
Founder and President, Yugen Research Organization, Undergraduate Student, Western Michigan University, MI, 49008 USA
Latyschev OY
IMA Academy President, RU

Abstract

Related the physio-pathological process of COVID-19 disease it is interesting to focus to the aspect.


Played by interaction of Sars-Cov-2 protein with integrins of human epithelial pulmonary cell.


A bio molecular approach help in to deeply verify the involved factors and the results of this Activation RGD mediated.


Of Great interest also the relationship with some vaccine strategy followed by the various pharmaceutical industry.


The results of this work will be useful to think modification in some vaccine increasing the global safety and related some rare ADR.

Article Details

M, L., Edbey, K., GR, M., AR, Y., & OY, L. (2021). OPEN and CLOSED state of SPIKE SARS-COV-2: relationship with some integrin binding. A biological molecular approach to better understand the coagulant effect. Archives of Biotechnology and Biomedicine, 5(1), 049–056. https://doi.org/10.29328/journal.abb.1001028
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Copyright (c) 2021 Luisetto M, et al.

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This work is licensed under a Creative Commons Attribution 4.0 International License.

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